Gidazepam | Analytical Reference Standard


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Are you seeking a verified, high-purity source for Gidazepam for laboratory use? Gidazepam is a unique atypical benzodiazepine derivative, developed for its selective anxiolytic properties with reduced sedative-hypnotic side effects. Within the scientific community, it is a primary subject for researchers investigating prodrug pharmacokinetics, the modulation of the GABA$_{A}$ receptor, and the development of high-resolution forensic detection assays.

We provide analytical-grade Gidazepam, verified via HPLC and LC-MS/MS to ensure the $\geq$98% purity required for rigorous in vitro pharmacological investigations and equipment calibration.


Pharmacological Profile & Mechanism of Action

Gidazepam is utilized as a sophisticated chemical probe to study the metabolic activation of 1,4-benzodiazepines. Researchers utilize this compound to explore:

  • Prodrug Activation: Investigating the hepatic metabolism of Gidazepam into its primary active metabolite, 7-bromo-5-phenyl-1,2-dihydro-3H-1,4-benzodiazepin-2-one (desalkylgidazepam).

  • Selective Anxiolysis: Researching the compound’s affinity for specific GABA$_{A}$ receptor subunits to understand why it exhibits potent anxiolytic effects while maintaining a lower profile for ataxia and sedation compared to diazepam.

  • Long-Term Kinetics: Studying the extended half-life of its metabolites, which makes it a subject of interest for steady-state concentration modeling.


Primary Research & Forensic Applications

Buy Gidazepam online is an essential reference material for several advanced scientific domains:

  • Forensic Toxicology: Serving as a validated reference standard (CAS: 129579-66-4) for identifying and quantifying the substance in biological matrices, particularly in jurisdictions where it is emerging as a Novel Psychoactive Substance (NPS).

  • Metabolic Mapping: Using high-purity standards to map the N-dealkylation pathways and identify specific biomarkers of exposure.

  • Analytical Method Development: Calibrating GC-MS and Orbitrap systems to differentiate Gidazepam from other brominated benzodiazepines.

  • Comparative Neuroscience: Utilizing Gidazepam as a structural baseline to evaluate the efficacy of other “atypical” anxiolytics.


Technical Specifications

Feature Details
IUPAC Name 2-(7-bromo-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-1-yl)acetohydrazide
CAS Number 129579-66-4
Molar Mass 387.23 g/mol
Purity Grade Analytical Reference Grade ($\geq$98%)
Molecular Formula $C_{17}H_{15}BrN_{4}O_{2}$

Safety, Regulatory Status, and Procurement

Gidazepam is intended strictly for authorized laboratory research and is not for human consumption.

  • Regulatory Compliance: While traditionally a prescription agent in specific regions, Gidazepam is often subject to “analog acts” or specific schedules in Western jurisdictions. Procurement requires valid institutional licensing and adherence to ECHA guidelines.

  • Handling & PPE: Due to its physiological activity, the use of Personal Protective Equipment (PPE), including nitrile gloves and eye protection, is mandatory.

  • Storage: Store in a cool, dry environment in airtight, light-resistant containers to maintain molecular stability.


Why Source Through Licensed Distribution Channels?

  • Verified Analytical Integrity: Every batch is independently tested to ensure materials meet the rigorous standards required for peer-reviewed research.

  • Chain of Custody: Professional logistics ensure tracked, secure shipping, maintaining the regulatory compliance required for institutional facilities.

  • Technical Documentation: Orders supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS).


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