Diazepam (Valium) | Analytical Reference Standard

Are you seeking a verified, high-purity source for Buy Diazepam online for laboratory use? Diazepam, widely known by the brand name Valium, is a long-acting benzodiazepine derivative. Within the scientific community, it is a primary subject for researchers investigating GABAergic neurotransmission, the pharmacology of anxiolysis, and the development of high-resolution forensic detection assays.

We provide analytical-grade Diazepam, verified via HPLC and GC-MS to ensure the $\geq$98% purity required for rigorous in vitro pharmacological investigations and equipment calibration.


Pharmacological Profile & Mechanism of Action

Diazepam is utilized as a foundational chemical probe to study the modulation of inhibitory signaling in the central nervous system. Researchers utilize this compound to explore:

  • Positive Allosteric Modulation: Investigating its binding to the benzodiazepine site located between the $\alpha$ and $\gamma$ subunits of the GABA$_{A}$ receptor.

  • Metabolic Pathway Analysis: Studying the conversion of diazepam into its active metabolites, including Nordiazepam, Temazepam, and Oxazepam.

  • Pharmacodynamic Diversity: Researching the compound’s multifaceted effects, including anxiolytic, anticonvulsant, and skeletal muscle relaxant properties.


Primary Research & Forensic Applications

Diazepam is an essential reference material for several advanced scientific domains:

  • Forensic Toxicology: Serving as a validated reference standard (CAS: 439-14-5) for identifying and quantifying the substance in complex biological matrices during post-mortem analysis.

  • Neuroscience Research: Exploring the impact of benzodiazepines on synaptic plasticity and the long-term modulation of the limbic system.

  • Analytical Method Development: Utilizing high-purity standards to calibrate LC-MS/MS systems for the ultra-sensitive detection of benzodiazepines.

  • Comparative Pharmacology: Using Diazepam as a “Gold Standard” baseline when evaluating the potency of novel designer benzodiazepines.


Technical Specifications

Feature Details
IUPAC Name 7-chloro-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one
CAS Number 439-14-5
Molar Mass 284.74 g/mol
Purity Grade Analytical Reference Grade ($\geq$98%)
Molecular Formula $C_{16}H_{13}ClN_{2}O$

Safety, Regulatory Status, and Procurement

Diazepam is a controlled substance and is intended strictly for authorized laboratory research.

  • Regulatory Compliance: In the US, Diazepam is a Schedule IV Controlled Substance. Procurement requires valid institutional licensing and adherence to ECHA and national narcotics laws.

  • Handling & PPE: Due to high physiological activity, the use of Personal Protective Equipment (PPE), including nitrile gloves and eye protection, is mandatory.

  • Storage: Store in a cool, dry environment in airtight, light-resistant containers.


Why Source Through Licensed Distribution Channels?

  • Verified Analytical Integrity: Every batch is independently tested to ensure materials of known concentration and high purity.

  • Chain of Custody: Professional logistics ensure tracked, secure shipping, maintaining the regulatory compliance required for institutional facilities.

  • Technical Documentation: Orders supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS).


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