Hydrocodone/Acetaminophen (Vicodin) | Analytical Reference Standard
Are you seeking a verified, high-purity source for Hydrocodone and Acetaminophen for laboratory use? Buy Vicodin Online, is a fixed-dose combination of a semi-synthetic opioid and a non-opiate analgesic. Within the scientific community, it is a primary subject for researchers investigating opioid receptor binding kinetics, hepatic metabolism, and the development of high-resolution forensic detection assays.
We provide analytical-grade Hydrocodone Bitartrate and Acetaminophen, verified via HPLC and LC-MS/MS to ensure the $\geq$98% purity required for rigorous in vitro pharmacological investigations and equipment calibration.
Pharmacological Profile & Mechanism of Action
Vicodin for sale UK is utilized as a sophisticated chemical probe to study the synergy between centrally acting opioids and peripherally acting analgesics. Researchers utilize this compound to explore:
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Mu-Opioid Agonism: Investigating Hydrocodone’s role as a potent agonist at the $\mu$-opioid receptor, which modulates ascending pain pathways and alters the perception of pain.
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COX Inhibition Modulation: Researching Acetaminophen’s potential inhibition of Cyclooxygenase (COX) enzymes in the central nervous system and its impact on prostaglandin synthesis.
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Synergistic Analgesia: Studying how the combination allows for effective pain management at lower opioid dosages, potentially reducing the risk of respiratory depression.
Primary Research & Forensic Applications
Vicodin components are essential reference materials for several advanced scientific domains:
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Forensic Toxicology: Serving as validated reference standards (CAS: 143-71-5 for Hydrocodone Bitartrate) for identifying and quantifying the substance and its primary metabolite, Hydromorphone, in biological matrices.
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Hepatotoxicity Studies: Investigating the mechanisms of Acetaminophen-induced liver injury through the production of the toxic metabolite NAPQI.
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Metabolic Mapping: Exploring the CYP2D6 and CYP3A4 mediated pathways responsible for the O-demethylation and N-demethylation of Hydrocodone.
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Method Validation: Utilizing high-purity standards to calibrate GC-MS systems for workplace drug testing and clinical screening.
Technical Specifications (Active Components)
| Feature | Hydrocodone Bitartrate | Acetaminophen (Paracetamol) |
| IUPAC Name | 4,5α-epoxy-3-methoxy-17-methylmorphinan-6-one tartrate | N-(4-hydroxyphenyl)acetamide |
| CAS Number | 143-71-5 | 103-90-2 |
| Molar Mass | 494.49 g/mol (Bitartrate) | 151.16 g/mol |
| Purity Grade | Analytical Grade ($\geq$98%) | Analytical Grade ($\geq$98%) |
| Formula | $C_{18}H_{21}NO_{3} \cdot C_{4}H_{6}O_{6}$ | $C_{8}H_{9}NO_{2}$ |
Safety, Regulatory Status, and Procurement
Vicodin components are controlled substances and are intended strictly for authorized laboratory research.
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Regulatory Compliance: In the US, Hydrocodone-containing products are Schedule II Controlled Substances. Procurement requires valid institutional licensing, DEA registration, and adherence to ECHA and national narcotics laws.
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Handling & PPE: Due to high physiological activity and opioid potency, the use of Personal Protective Equipment (PPE), including nitrile gloves and a certified fume hood, is mandatory.
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Storage: Store in a cool, dry, and light-protected environment to maintain molecular stability.
Why Source Through Licensed Distribution Channels?
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Verified Analytical Integrity: Every batch is independently tested to ensure materials meet the rigorous standards required for peer-reviewed research.
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Chain of Custody: Professional logistics ensure tracked, secure shipping, maintaining the regulatory compliance required for institutional facilities.
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Technical Documentation: Orders supported by batch-specific Certificates of Analysis (COA) and Safety Data Sheets (SDS).
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