Buy 3-MeO-PCE (3-Methoxyeticyclidine): A Technical Overview

Buy 3-MeO-PCE (3-Methoxyeticyclidine) is a synthetic arylcyclohexylamine and a potent dissociative research compound. While it shares structural similarities with PCE and PCP, it is specifically utilized in controlled laboratory settings for spectroscopic analysis and pharmacological profiling.

Chemical Properties & Specifications

For analytical laboratories requiring precise reference data, the following specifications define the 3-MeO-PCE compound:

Parameter	Value
IUPAC Name	N-Ethyl-1-(3-methoxyphenyl)cyclohexan-1-amine
Molecular Formula	$C_{15}H_{23}NO$
Molecular Mass	233.355 g/mol
CAS Number	1364933-80-1
Chemical Class	Dissociative Arylcyclohexylamine

Molecular Structure

SMILES: CCNC1(CCCCC1)C2=CC(=CC=C2)OC
InChI: 1S/C15H23NO/c1-3-16-15(10-5-4-6-11-15)13-8-7-9-14(12-13)17-2/h7-9,12,16H,3-6,10-11H2,1-2H3

Pharmacology and Receptor Affinity

3-MeO-PCE acts primarily as an NMDA receptor antagonist, with significant affinity for the PCP binding site. Recent in-silico and in-vitro studies have mapped its binding profile ( $K_i$ values) as follows:

NMDA Receptor: 61 nM (Primary mechanism of action)
Serotonin Transporter (SERT): 115 nM
Dopamine Transporter (DAT): 743 nM
Sigma Receptors: $\sigma_1$ (4519 nM) and $\sigma_2$ (525 nM)
Alpha-2A-Adrenergic Receptor: 964 nM

Physiological and Psychoactive Profile

As a dissociative anesthetic, 3-MeO-PCE induces altered sensory perception and hallucinations. Researchers have noted a higher affinity for the serotonin transporter compared to other PCP analogues, potentially contributing to its unique stimulant-like properties in certain experimental models.

European Regulatory Landscape (2026 Update)

The legal status of 3-MeO-PCE varies significantly across European jurisdictions. Compliance with local legislation is mandatory for all distribution and research.

Netherlands: Currently monitored under the Opium Act. While widely discussed in the “grey market,” institutional researchers must verify updated 2026 bans on arylcyclohexylamine groups before procurement.

IGermany: Regulated under the NpSG (New Psychoactive Substances Act). Authorized for industrial and scientific research only; possession for non-scientific use is prohibited.
United Kingdom: Classified as a Class B drug under the Misuse of Drugs Act via the catch-all clause for arylcyclohexylamines.
Sweden & Switzerland: Strictly prohibited; categorized as an illegal narcotic.

Scientific Inquiry & Laboratory Safety

Due to its potency and potential to induce psychotic disorders in non-controlled environments, 3-MeO-PCE is designated for in-vitro laboratory research only.

Professional sourcing through specialized vendors like EUChems ensures that analytical institutions receive materials that are:

Independently Lab-Tested: $\ge$ 98% purity confirmed via HPLC/MS.
Fully Documented: Accompanied by relevant Safety Data Sheets (SDS) and batch analysis.
Securely Shipped: Vacuum-sealed and tracked for institutional reliability.

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