Buy 5F-MDMB-2201 Powder | High-Purity Synthetic Cannabinoid for Research
Are you seeking a verified source to buy 5F-MDMB-2201 powder? 5F-MDMB-2201 (also known as 5F-MDMB-PICA) is a highly potent synthetic cannabinoid of the indazole-3-carboxamide class. As a fluorinated analog of MDMB-PICA, this compound is a primary subject for researchers investigating the pharmacodynamics of the endocannabinoid system (ECS) and the forensic identification of novel psychoactive substances (NPS).
We provide high-purity 5F-MDMB-2201 powder, rigorously tested to ensure the analytical grade ($\geq$98%) necessary for consistent results in receptor-binding assays and metabolic profiling.
What is 5F-MDMB-2201?
5-Fluoro-MDMB-PICA is a tert-leucinate-derived indazole synthetic cannabinoid. It is distinguished by its 5-fluoropentyl chain and its status as a potent full agonist at both the CB1 and CB2 receptors. Because of its extreme potency compared to traditional cannabinoids, it is a critical molecule for mapping high-affinity receptor-ligand interactions.
Pharmacological Profile
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Mechanism of Action: Acts as a high-efficacy full agonist at the CB1 and CB2 receptors.
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Receptor Affinity: Studies suggest an $EC_{50}$ value significantly lower than that of $\Delta^9$-THC, marking it as a subject of interest for potency threshold research.
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Chemical Class: Indazole-3-carboxamide / Fluorinated Synthetic Cannabinoid.
Primary Research Applications
5F-MDMB-2201 is an essential tool for advanced scientific inquiry:
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Receptor-Binding Assays: Measuring the binding efficiency and intrinsic activity at cannabinoid receptors in preclinical models.
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Metabolic Pathway Mapping: Investigating the in-vitro degradation and identification of metabolite markers to assist in forensic screening (GC-MS, LC-MS/MS).
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Neurochemical Studies: Exploring the compound’s impact on neurotransmitter release and its role in modulating the central nervous system.
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Analytical Standardization: Serving as a high-purity reference standard for forensic toxicology and academic laboratories.
Technical Specifications
| Feature | Details |
| IUPAC Name | methyl 2-[[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3-dimethyl-butanoate |
| Common Names | 5F-MDMB-2201, 5F-MDMB-PICA, MDMB-2201 |
| Molecular Formula | $C_{21}H_{29}FN_{2}O_{3}$ |
| Molecular Weight | 376.47 g/mol |
| Purity Grade | $\geq$98% (Analytical Grade) |
| Physical Form | Fine Crystalline Powder |
Safety, Handling, and Laboratory Precautions
5F-MDMB-2201 is strictly intended for laboratory, academic, and forensic research. It is NOT for human or veterinary consumption.
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Safety Protocols: Researchers must utilize appropriate Personal Protective Equipment (PPE), including nitrile gloves, lab coats, and safety goggles. A Safety Data Sheet (SDS) is included with every order.
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Storage: Store in a cool, dry, and dark environment in a clearly labeled, airtight container to maintain compound stability and prevent degradation.
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Legal Compliance: 5F-MDMB-2201 is a Schedule I controlled substance in the United States and is heavily regulated globally (e.g., UN Psychotropic Schedule II). Procurement is only available to qualified institutions and authorized researchers.
Why Choose Our 5F-MDMB-2201?
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Guaranteed Chemical Identity: Every batch is verified via HPLC and NMR to ensure the highest purity and zero synthesis byproducts.
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Secure Professional Fulfillment: We prioritize prompt, discreet, and reliable delivery to accredited research laboratories worldwide.
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Institutional Support: We provide comprehensive documentation, including a Certificate of Analysis (COA), to support institutional compliance.
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